Puppy Vaccination Schedule 2025: What You Need
Getting a new puppy means many vet visits. Vaccinations are critical because puppies have zero immunity once their mother's milk antibodies fade.
The Timeline
6-8 Weeks: The First Round
- DHPP (Core): Distemper, Hepatitis, Parvovirus, Parainfluenza.
- Why?: Parvo kills puppies in 48 hours. This is non-negotiable.
- Bordetella (Non-Core): Kennel Cough. Recommended if you plan to board or go to puppy class.
10-12 Weeks: The Booster
- DHPP: Round 2 of the core shot.
- Leptospirosis: Protects against bacteria in puddle water/rat urine. Highly recommended in cities and farms.
- Lyme: If you live in tick country (Northeast/Midwest US).
- Influenza: Current strains H3N2/H3N8.
16 Weeks: The Final Puppy Shots
- DHPP: Round 3 (Final Booster).
- Rabies (Core): Legally Required in almost every state/country. Usually a 1-year vaccine first.
The "Immunity Gap"
Between 8 and 16 weeks, your puppy is vulnerable.
- Don't: Go to public dog parks or PetSmart floors.
- Do: Socialize with known, vaccinated adult dogs in private backyards.
The "Titers" Alternative
Some owners prefer to test antibody levels (Titers) instead of boosting annually. This is valid for Distemper/Parvo, but Rabies laws usually require the shot regardless of titer levels.
Side Effects
It is normal for a puppy to be sleepy for 24 hours after shots.
- Emergency: Swollen face (hives) or vomiting within 1 hour. This is an allergic reaction. Go back to the vet.