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Cat Lump on Side of Neck: When to Biopsy

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Dr. Emily WhiskerFeline Oncologist
calendar_today2025-12-29schedule5 min read
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Cat Lump on Side of Neck: When to Biopsy

Cat Lump on Side of Neck: When to Biopsy

You are petting your cat and your finger hits a bump. Panic sets in. Wait. 90% of neck lumps in outdoor cats are not cancer.

The #1 Cause: Cat Bite Abscess

If your cat goes outside, they likely got into a fight.

  • The Feel: Soft, fluid-filled, hot to the touch.
  • The Behavior: The cat flinches (it hurts).
  • Treatment: It needs to be lanced and drained by a vet + antibiotics.

The #2 Cause: Swollen Lymph Nodes

Just like you get swollen glands when you have a cold, cats get submandibular lymph node swelling from dental infections.

  • The Feel: Firm, movable (like a grape under the skin), usually on both sides.
  • Treatment: Dental cleaning/extraction of the rotten tooth.

The #3 Cause: Injection Site Sarcoma (ISS)

This is the bad one. If the lump is at the site of a previous vaccine (usually lower down the neck/shoulder).

  • The Rule (3-2-1 Rule): Biopsy if:
    1. Persists for 3 months.
    2. Is larger than 2 cm.
    3. Increases in size 1 month after vaccination.

The #4 Cause: Thyroid Tumor

Small nodule on the windpipe.

  • Sign: Cat is losing weight but eating voraciously (Hyperthyroidism).

Conclusion

If it's hot and painful -> Abscess. If it's hard and growing -> Biopsy ASAP.

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About This Article

This article was researched from authoritative veterinary sources including the AVMA, ASPCA, and peer-reviewed veterinary journals. While we strive for accuracy, this information is for educational purposes only and should not replace professional veterinary advice.

Always consult your veterinarian for medical concerns about your pet.

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